There are many conceivable ways to map 52edo onto the onto the Lumatone keyboard. However, it has 2 mutually-exclusive rings of fifths, so the Standard Lumatone mapping for Pythagorean is not one of them.
Diatonic
You can use the b val, which produces Dirt, but the fifth is extremely sharp, to the point where major seconds become 8/7 instead of 9/8 and the best approximation to 5/4 is a doubly augmented 7th.
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Neutral thirds
The neutral thirds mapping is probably easier to navigate.
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Pseudo-Pentacircle
Bryan Deister has used a layout for 52edo in which the generator is 9\52, as ~9/8 but mapped by direct approximation rather than as the version mapped by the patent val or by the 52b val, which means that it has to be constituted as (3♭ × 3♯) / 8 to make use of the dual-fifth feature of 52edo. Two of these map to a ~14/11 major third, as in Pentacircle but for the direct approximation mapping of ~9/8. The upward generator is ~16/15. Octaves slant down and then wrap around, but the compass is 5 full octaves, with no missed notes, which is competitive with the Diatonic and Neutral Thirds layouts. This layout is demonstrated in microtonal improvisation in 52edo (2025); in the video, some notes are cut off at the right edge due to the use of only 2 MIDI channels.
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