ABC, High Quality Commas, and Epimericity
If n/d > 1 is a rational number with positive integers n and d relatively prime, we may define the epimericity of n/d as log(n-d)/log(d). Which logarithm we use is irrelevant; we can if we like use cents and so the epimericity is also cents(n-d)/cents(d). Then it appears to be true that Størmer's theorem generalizes to a claim that for any prime p, only finitely many rational numbers in the p-limit exist with epimericity less than or equal to any constant c less than one. Hence "interesting" commas in any p-limit can be defined as those below a given epimericity, such as the 7-limit commas under 0.5 in epimericity, or the 11-limit commas under 0.3.
The ABC conjecture
This conjecture is related to the abc conjecture, and a related claim is in fact precisely the abc conjecture, which defines what we may call a high quality comma. Define the radical rad(n/d) of n/d as the product of all the primes dividing n, d, and n-d; so that rad(128/125) = 2*3*5 = 30. Then define the quality q(n/d) of n/d as log(n)/log(rad(n/d)). Then the abc conjecture, a very powerful conjecture, says that for any ϵ > 0 there are only finitely many commas such that q(n/d) > 1+ϵ, where we may assume without loss of generality that n/d < 2 so that it is an actual comma. Any comma with q(n/d) > 1 we may call "high quality"; there are an infinite number of these, but the conjecture is that there are only finitely many above any value greater than 1. High quality commas in the 5-limit include 250/243, 128/125, 3125/3072, 81/80 and 2048/2025. It should be noted that while every superparticular ratio has an epimericity of 0, merely being superparticular is by no means enough to make a comma high quality; the list of high-quality superparticulars starts 9/8, 49/48, 64/63, 81/80, 225/224, 243/242 ... .
The DoReMi conjecture
Since not much musical meaning seems to attach to the commas dividing n-d, it makes sense for our purposes to modify the definition of quality. Let doremi(n/d) = log(n)/log((n-d)radical(nd)), where radical(nd) is the product of the primes dividing nd. Then q(n/d) ≤ doremi(n/d), so that the condition that doremi(n/d) > 1+ϵ is stronger than q(n/d) > 1+ϵ, and there will be fewer intervals which qualify. This means that if the list of q(n/d) > 1+ϵ is finite, so is the list of doremi(n/d) > 1+ϵ. So ABC implies DoReMi but the converse is not true; DoReMi is a slightly weaker conjecture that is also unproven (according to Noam Elkies and Stack Overflow ). Aside from its clearer music theory implications, DoReMi is enormously easier to compute if n/d is in some small p-limit, as then the computation of radical(nd) involves only small primes. A comma n/d with doremi(n/d) > 1 may be called a DoReMi comma.
The DoReMi commas with numerator less than 1000 are 32/27, 9/8, 256/243, 250/243, 128/125, 49/48, 64/63, 81/80, 512/507, 245/243, 225/224, 243/242, 289/288, 513/512, 625/624, 676/675, 729/728 and 961/960. Note that large powers of small primes are favored, so that commas such as 512/507 are on the list.