49ed6 divides the just 6:1 into 49 equal parts, resulting in a step size of about 63.3053 cents and an octave approximately 3 cents sharp. It is a stretched version of 19edo and extremely close to the zeta peak, thus minimizing relative error as much as possible. Because 19edo itself is a flat-tending system, stretching the octave by this much improves the overall tuning accuracy.
The fifth is ~ 696.36 cents; about 1/4 of a cent flatter than the fifth of quarter-comma meantone, or half a cent flatter than the fifth of 31edo. The fourth is less accurate than in 19edo, and is close in size to a flattone fourth.
Minor thirds are still excellent, only slightly less accurate than they are in standard 19edo.
Usable prime harmonics include the 3:1 (about 3 cents flat), the 5:1 (about a cent flat), and the 7:1 and 13:1 (around 12 and 9 cents flat, respectively). The 7:1 and 13:1 in particular are much improved; with pure octaves they are too far out of tune to be usable for most, but the situation changes with the stretched version.
Other variants (which stretch the octave slightly more, but the differences are probably imperceptible) are 44ed5 and 93ed30. The latter of the two optimizes the accuracy of the 1:5:6 triad, since the 5 is as flat as the 6 is sharp.
Tunings in this range are a promising option for stiff-stringed instruments since they have stretched partials, and the most noticeable partial is the 2nd; thus, a piano tuned to have beatless octaves will actually have them around 1203 cents or so (depending on string length), which coincidentally is very close to what the zeta-optimal stretched version of 19edo has.