If one attempts to use 2edo as an actual scale, it would divide the octave into two equal parts, each of size 600 cents, which is to say sqrt(2) as a frequency ratio. The harmony that is found in 2edo can be said to revolve around Tonic-Antitonic contrast, with the note at 600 cents away from the Tonic having a function akin to 12edo's diminished fifth.

If we want to consider it to be a temperament, it tempers out 9/8, meaning that it supports antitonic- a temperament named based on the functionality of the 600 cent interval relative to the Tonic. In fact, it even supports both the 7-limit and 11-limit extensions of antitonic as it also tempers out both 15/14 and 12/11 respectively. However, the significance of 9/8 in particular being less than half the size of a single step should not be underestimated, as because of this, 2edo is the first EDO to demonstrate 3-to-2 telicity. It represents the 3-limit consistently, and it can be used to give a skeletonized version of the 3-limit music such as was used in Medieval Europe, by mapping the fifth and therefore the fourth to 600 cents. That entails mapping 81/64 to the unison, and if we do the same for 5/4 we end up with the val <2 3 4| (2c mapping). This could be used to crush all of the 5 out of 5-limit music, and to then attempt to turn what remains into neo-Medieval harmony.

Factoids about 2EDO

Compositions

Dichotomy by Kaiveran Lugheidh